Structure of PDB 5zth Chain A Binding Site BS01

Receptor Information
>5zth Chain A (length=453) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVN
KKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQV
KDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKN
SHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVV
RRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTN
AIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDF
AELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLN
KITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTG
ADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLS
KLD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zth Unveiling the structural features that determine the dual methyltransferase activities of Streptococcus pneumoniae RlmCD
Resolution3.24 Å
Binding residue
(original residue number in PDB)		G79 I80 R127 K129 Q131 F145 F146 R147 K148 N149 S150 H151 N249 I251 F281 Q283 D381 P382 R384 K385 C408 F436 H441 Q443
Binding residue
(residue number reindexed from 1)		G80 I81 R128 K130 Q132 F146 F147 R148 K149 N150 S151 H152 N250 I252 F282 Q284 D382 P383 R385 K386 C409 F437 H442 Q444
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0008173 RNA methyltransferase activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:5zth, PDBe:5zth, PDBj:5zth
PDBsum5zth
PubMed30388185
UniProtQ97R12|Y1029_STRPN Uncharacterized RNA methyltransferase SP_1029 (Gene Name=SP_1029)

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