Structure of PDB 5zta Chain A Binding Site BS01

Receptor Information
>5zta Chain A (length=254) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLELQEPTIET
GFEACVKQGATHIAVVPLLLLTAAHAKHDIPEEIVRVASRYPSVRISYGK
PIGIDEEVVKAVYHRMKDIGVPYENARVVLIGRGSSDPDVKRDVTGIANL
LQEMVPVKEVIPCFLTACGPNYKEVFSELEKDDGITTFIVPYLLFTGMLM
NEIEREVQKLKAHNPNVYLSSYIGFHPHVKNAFLNRVRETAANSEGQFDF
DGGS
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain5zta Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5zta A route for metal acquisition for chelatase reaction catalyzed by SirB from Bacillus subtilis
Resolution3.07 Å
Binding residue
(original residue number in PDB)		H115 H229
Binding residue
(residue number reindexed from 1)		H114 H228
Annotation score1
Enzymatic activity
Enzyme Commision number 4.99.1.4: sirohydrochlorin ferrochelatase.
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0051266 sirohydrochlorin ferrochelatase activity
Biological Process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0019354 siroheme biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5zta, PDBe:5zta, PDBj:5zta
PDBsum5zta
PubMed
UniProtO34632|SIRB_BACSU Sirohydrochlorin ferrochelatase (Gene Name=sirB)

[Back to BioLiP]