Structure of PDB 5zqg Chain A Binding Site BS01

Receptor Information
>5zqg Chain A (length=292) Species: 28295 (Porcine epidemic diarrhea virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDTVMCPRHVIAIDYDYA
LSVLRLHNFSISSGNVFLGVVGVTMRGALLQIKVNQNNVHTPKYTYRTVR
PGESFNILACYDGAAAGVYGVNMRSNYTIRGSFINGAAGSPGYNINNGTV
EFCYLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASSLFTENVLAF
LYAALINGSTWWLSSSRIAVDRFNEWAVHNGMTTVVNTDCFSILAAKTGV
DVQRLLASIQSLHKNFGGKQILGYTSLTDEFTTGEVIRQMYG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zqg Complex structure of PEDV 3CLpro mutant (C144A) with NEMO peptite substrate
Resolution1.6 Å
Binding residue
(original residue number in PDB)		M25 A26 H41 F139 G142 A143 A144 H162 Q163 L164 E165 D186 T189
Binding residue
(residue number reindexed from 1)		M25 A26 H41 F133 G136 A137 A138 H156 Q157 L158 E159 D180 T183
Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

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Molecular Function
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Biological Process
External links
PDB RCSB:5zqg, PDBe:5zqg, PDBj:5zqg
PDBsum5zqg
PubMed
UniProtR4JK63

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