Structure of PDB 5zq8 Chain A Binding Site BS01

Receptor Information
>5zq8 Chain A (length=454) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNK
KIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVK
DSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNS
HNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVR
RGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNA
IFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFA
ELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNK
ITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGA
DRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLSK
LDVD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5zq8 Unveiling the structural features that determine the dual methyltransferase activities of Streptococcus pneumoniae RlmCD
Resolution2.18 Å
Binding residue
(original residue number in PDB)		G79 R127 K129 A130 Q131 P133 F145 F146 K148 N149 S150 H151 I161 Q162 E187 N249 I251 F281 Q283 D381 P382 R384 K385 C408 F436 H441 Q443
Binding residue
(residue number reindexed from 1)		G79 R127 K129 A130 Q131 P133 F145 F146 K148 N149 S150 H151 I161 Q162 E187 N249 I251 F281 Q283 D381 P382 R384 K385 C408 F436 H441 Q443
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0008173 RNA methyltransferase activity
Biological Process
GO:0006396 RNA processing

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5zq8, PDBe:5zq8, PDBj:5zq8
PDBsum5zq8
PubMed30388185
UniProtQ97R12|Y1029_STRPN Uncharacterized RNA methyltransferase SP_1029 (Gene Name=SP_1029)

[Back to BioLiP]