Structure of PDB 5zq0 Chain A Binding Site BS01

Receptor Information
>5zq0 Chain A (length=453) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVN
KKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQV
KDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKN
SHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVV
RRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTN
AIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDF
AELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLN
KITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTG
ADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVQTVALLS
KLD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zq0 Unveiling the structural features that determine the dual methyltransferase activities of Streptococcus pneumoniae RlmCD
Resolution2.0 Å
Binding residue
(original residue number in PDB)
S78 G79 R127 K129 A130 Q131 P133 F145 F146 K148 N149 S150 H151 I161 Q162 E187 N249 I251 F281 Q283 D381 P382 R384 C408 F436 H441 Q443
Binding residue
(residue number reindexed from 1)
S79 G80 R128 K130 A131 Q132 P134 F146 F147 K149 N150 S151 H152 I162 Q163 E188 N250 I252 F282 Q284 D382 P383 R385 C409 F437 H442 Q444
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0008173 RNA methyltransferase activity
Biological Process
GO:0006396 RNA processing

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Molecular Function

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Biological Process
External links
PDB RCSB:5zq0, PDBe:5zq0, PDBj:5zq0
PDBsum5zq0
PubMed30388185
UniProtQ97R12|Y1029_STRPN Uncharacterized RNA methyltransferase SP_1029 (Gene Name=SP_1029)

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