Structure of PDB 5zcy Chain A Binding Site BS01

Receptor Information
>5zcy Chain A (length=83) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLKEQQRIKVYIERARYGKVKTIIEGIDEKEFDLEEIAKKLKAKLACGGT
AKNGRIELQGDHRDRIKKLLAELGFSEELIEVE
Ligand information
Ligand IDNO2
InChIInChI=1S/HNO2/c2-1-3/h(H,2,3)/p-1
InChIKeyIOVCWXUNBOPUCH-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
[O-]N=O
OpenEye OEToolkits 1.5.0N(=O)[O-]
FormulaN O2
NameNITRITE ION
ChEMBL
DrugBankDB12529
ZINC
PDB chain5zcy Chain A Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zcy Archaeal and eukaryal translation initiation factor 1 differ in their RNA interacting loops.
Resolution1.5 Å
Binding residue
(original residue number in PDB)
R30 A31
Binding residue
(residue number reindexed from 1)
R14 A15
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0002188 translation reinitiation
GO:0006412 translation
GO:0006413 translational initiation
GO:0006417 regulation of translation

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Molecular Function

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Biological Process
External links
PDB RCSB:5zcy, PDBe:5zcy, PDBj:5zcy
PDBsum5zcy
PubMed29608219
UniProtP58193|SUI1_PYRHO Protein translation factor SUI1 homolog (Gene Name=PH1771.1)

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