Structure of PDB 5zb3 Chain A Binding Site BS01

Receptor Information
>5zb3 Chain A (length=280) Species: 37296 (Human gammaherpesvirus 8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRLPASMIIDGESPRFDDSIIPRHHGACFNVFIPAPPSHVPEVFTDRDIT
ALIRAGGKDDELINKKISAKKIDHLHRQMLSFVTSRHNQAYWVSCRRETA
AAGGLQTLGAFVEEQMTWAQTVVRHGGWFDEKDIDIILDTAIFVCNAFVT
RFRLLHLSCVFDKQSELALIKQVAYLVAMGNRLVEACNLLGEVKLNFRGG
LLLAFVLTIPGMQSRRSISARGQELFRTLLEYYRPGDVMGLLNVIVMEHH
SLCRNSECAAATRAAMGSAKFNKGLFFYPL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5zb3 Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5zb3 The crystal structure of KSHV ORF57 reveals dimeric active sites important for protein stability and function.
Resolution3.506 Å
Binding residue
(original residue number in PDB)
C333 H423 C427 C432
Binding residue
(residue number reindexed from 1)
C159 H249 C253 C258
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5zb3, PDBe:5zb3, PDBj:5zb3
PDBsum5zb3
PubMed30096191
UniProtQ2HR75|MTA_HHV8P Post-transcriptional regulator MTA (Gene Name=ORF57)

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