Structure of PDB 5z8y Chain A Binding Site BS01

Receptor Information
>5z8y Chain A (length=328) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFAS
FSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLI
NLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSL
EFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHT
LFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILL
MDNNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRW
EHSILCHSPDHTQGEDILDAVAGFQLCW
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5z8y Chain A Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5z8y Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		H53 H72
Binding residue
(residue number reindexed from 1)		H20 H39
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5z8y, PDBe:5z8y, PDBj:5z8y
PDBsum5z8y
PubMed30262834
UniProtO43300|LRRT2_HUMAN Leucine-rich repeat transmembrane neuronal protein 2 (Gene Name=LRRTM2)

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