Structure of PDB 5z4a Chain A Binding Site BS01

Receptor Information
>5z4a Chain A (length=351) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMQHITVRLPKKARAMIVGEITNVFKDKYPIADKLKVIPEYDVIEQDLCK
LLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGNTFHTFEHRASNA
TVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLNSM
GFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQISTYSITLMVIYF
LQLQALLPPIAMLQIEDAANQAVLVGPWVVNFAQKSFSELGLQQLKATVP
VIKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYVS
DNPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTFVDYCQQTAELLEE
P
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5z4a Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Resolution1.637 Å
Binding residue
(original residue number in PDB)
D278 D280 I323 A326 R327 V328 D343 N347 G350 N353 Y390
Binding residue
(residue number reindexed from 1)
D79 D81 I124 A127 R128 V129 D144 N148 G151 N154 Y191
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
External links
PDB RCSB:5z4a, PDBe:5z4a, PDBj:5z4a
PDBsum5z4a
PubMed30407553
UniProtQ9VI58|TUTT_DROME Terminal uridylyltransferase Tailor (Gene Name=Tailor)

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