Structure of PDB 5yox Chain A Binding Site BS01

Receptor Information
>5yox Chain A (length=183) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WKPEDNIPREILAILSKPHPNYQLAFLNIIQLLKTQRSISDHMYRMGLTT
MLITDKNVDRNKCIRIALVHDFAESLVKEEKHRREFETVKYLCESIIRPC
SESASREILDDWLAYEKQTCLEGRYVKDIDKYEMLVQCFEYEQKYNGKKD
LKQFLGAINDIKTDEVKKWTQSLLEDRQAFFDS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5yox Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5yox HD domain-containing protein YGK1(YGL101W)
Resolution2.61 Å
Binding residue
(original residue number in PDB)		H61 H89 D90 D159
Binding residue
(residue number reindexed from 1)		H42 H70 D71 D130
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.89: 5'-deoxynucleotidase.
Gene Ontology
Molecular Function
GO:0002953 5'-deoxynucleotidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050484 GMP 5'-nucleotidase activity
Biological Process
GO:0009159 deoxyribonucleoside monophosphate catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5yox, PDBe:5yox, PDBj:5yox
PDBsum5yox
PubMed
UniProtP53144|YGK1_YEAST 5'-deoxynucleotidase YGK1 (Gene Name=YGK1)

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