Structure of PDB 5yko Chain A Binding Site BS01

Receptor Information

>5yko Chain A (length=487) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RWNPSEACRPLVDDAPIFYPTNEDFDDPLGYIEKLRSKAESYGICRIVPP
VAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNRFGFQTGPDFTLAAFQKY
DEYFKECYFQPKVKDLEGEYWRIVEQATDEVEVYYGADLETKKFGSGFPK
YKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGVIVPWLYVGM
CFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDL
FEEQPDLLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFN
CGFNCAEAVNVAPVDWLVHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEAT
YCLWELSLSKKKTPVIARWKRVCSEDGLLTKAVKKRVQMEEERLNHLQDG
FSLRKMEGDFDNKRERECFLCFYDLHMSASSCKCSPNRFACLIHAKDLCS
CESKDRYILIRHTLDELWALVRALEGDLDAIDLWASK

Ligand information

>5yko Chain P (length=7) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ARTKQTA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5yko Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	D239 W296 E311 D312 Q361 L362 V410 N411 S436 E516
Binding residue (residue number reindexed from 1)	D138 W195 E210 D211 Q260 L261 V309 N310 S335 E415

Enzymatic activity

Enzyme Commision number

1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.

External links

PDB	RCSB:5yko, PDBe:5yko, PDBj:5yko
PDBsum	5yko
PubMed	29233856
UniProt	Q8GUI6\|JMJ14_ARATH Lysine-specific demethylase JMJ14 (Gene Name=JMJ14)

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