Structure of PDB 5yk6 Chain A Binding Site BS01

Receptor Information
>5yk6 Chain A (length=239) Species: 559307 (Zygosaccharomyces rouxii CBS 732) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NERSRQIDDILEKTYYNVDTHPAESLDWFNVLIGQTIQQLREEAWKKDNI
VYSLNAFIERKAQELPSYLDSIKITELDIGHDFPIFSNCRIQYSPNSNGR
KLEAKIDIDLNDRLAVGIETRLLLNYPKPLTASLPINVTVSIIRFQACLT
VSLTKAEEFVPTSPNDGYFLMFSFAPEYRMEFETQSLIGARSKLENIPKI
GSLVEYQIKKWFVERCVEPRFQFIKLPSVWPRSKNTREG
Ligand information
Ligand ID3PH
InChIInChI=1S/C39H77O8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h37H,3-36H2,1-2H3,(H2,42,43,44)/t37-/m1/s1
InChIKeyYFWHNAWEOZTIPI-DIPNUNPCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCCCC
OpenEye OEToolkits 1.5.0CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCCCC
ACDLabs 10.04O=P(O)(OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)O
CACTVS 3.341CCCCCCCCCCCCCCCCCC(=O)OC[CH](CO[P](O)(O)=O)OC(=O)CCCCCCCCCCCCCCCCC
CACTVS 3.341CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO[P](O)(O)=O)OC(=O)CCCCCCCCCCCCCCCCC
FormulaC39 H77 O8 P
Name1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE;
PHOSPHATIDIC ACID
ChEMBL
DrugBank
ZINCZINC000058632461
PDB chain5yk6 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5yk6 Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		W430 R432 S433
Binding residue
(residue number reindexed from 1)		W230 R232 S233
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007005 mitochondrion organization
Cellular Component
GO:0032865 ERMES complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5yk6, PDBe:5yk6, PDBj:5yk6
PDBsum5yk6
PubMed29078410
UniProtC5DRQ1|MMM1_ZYGRC Maintenance of mitochondrial morphology protein 1 (Gene Name=MMM1)

[Back to BioLiP]