Structure of PDB 5yd0 Chain A Binding Site BS01

Receptor Information
>5yd0 Chain A (length=327) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGLEVLFQGPHMGGSPDLIIHAGEVTLGEKDRNKMDSKKKRLEKARITEA
ACALLNSGGGVIVMQMSNKSEHPVEMGLDLETSLRELIPSSDLQAFIETK
QQGDLFYIFVKSWSTKPRICSLSSSLYCRSLTSKLPLDSKETFEFLERKK
TCVKNDLESNPAFEIFQSERLEYGQRLPFSESASIEFKQFSTRRAHEYIK
SVIPEYISAFANTQGGYLLFGVDDESKRVLGCPKDNVDRDSLKAVVNEAI
SKLPVFHFCSSKEKVSYKTRVIDVFKEGNLYGYLCVIKVERFCCAVFSEA
PISWMADKENGVYSLNTEKWVRMMVDI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5yd0 Chain A Residue 900 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5yd0 Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control
Resolution3.182 Å
Binding residue
(original residue number in PDB)
H281 C317 C318
Binding residue
(residue number reindexed from 1)
H257 C293 C294
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
External links
PDB RCSB:5yd0, PDBe:5yd0, PDBj:5yd0
PDBsum5yd0
PubMed29563550
UniProtQ5U311|SLN13_RAT Schlafen family member 13 (Gene Name=Slfn13)

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