Structure of PDB 5ybe Chain A Binding Site BS01

Receptor Information
>5ybe Chain A (length=254) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPEKEEIRERYELSEKMLSACNLLKYNIKDPKALASKDMRICLNTLQHDW
FRVSSQKSAVPAMVGDYIAAFEAVSPDVLRYIINMADGNGNTALHYSVSH
SNFQIVKLLLDADVCNVDHQNKAGYTPIMLAALAAVEAEKDMQVVEELFS
CGDVNAKASQAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALM
CASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYA
HLNF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ybe Structural analyses of key features in the KANK1/KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex.
Resolution2.111 Å
Binding residue
(original residue number in PDB)		N1169 N1171 S1179 N1201 K1202 A1203 Y1205 M1209 L1210 L1213 L1248 H1252 E1274 S1276 E1284 H1285 D1306 D1308 I1315
Binding residue
(residue number reindexed from 1)		N89 N91 S99 N121 K122 A123 Y125 M129 L130 L133 L168 H172 E194 S196 E204 H205 D226 D228 I235
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0030837 negative regulation of actin filament polymerization

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Biological Process
External links
PDB RCSB:5ybe, PDBe:5ybe, PDBj:5ybe
PDBsum5ybe
PubMed29158259
UniProtQ6AXG6

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