Structure of PDB 5yay Chain A Binding Site BS01

Receptor Information
>5yay Chain A (length=244) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RYELSEKMLSACNLLKYNIKDPKALASKDMRICLNTLQHDWFRVSSQKSA
VPAMVGDYIAAFEAVSPDVLRYIINMADGNGNTALHYSVSHSNFQIVKLL
LDADVCNVDHQNKAGYTPIMLAALAAVEAEKDMQVVEELFSCGDVNAKAS
QAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALMCASEHGHVE
IVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHLN
Ligand information
Receptor-Ligand Complex Structure
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PDB5yay Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.
Resolution1.55 Å
Binding residue
(original residue number in PDB)
N1169 N1171 Y1176 N1201 A1203 Y1205 L1210 L1213 Q1243 H1252 E1274 S1276 C1281 E1284 D1306 D1308 I1315
Binding residue
(residue number reindexed from 1)
N80 N82 Y87 N112 A114 Y116 L121 L124 Q154 H163 E185 S187 C192 E195 D217 D219 I226
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0030837 negative regulation of actin filament polymerization

View graph for
Biological Process
External links
PDB RCSB:5yay, PDBe:5yay, PDBj:5yay
PDBsum5yay
PubMed29217769
UniProtE9Q238

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