Structure of PDB 5y7f Chain A Binding Site BS01

Receptor Information
>5y7f Chain A (length=267) Species: 28565 (Thermomyces dupontii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADINIFSVASGHLYERMLNIMMVSVMKHTKHSVKFWFIEQFLSPSFKKFL
PHLAKEYGFSYEMVTYKWPHWLRGQREKQREIWGYKILFLDVLFPLSLDK
VIFVDADQIVRTDMYDLVQLDLEGAPYGFTPMCDSRKEMEGFRFWKQGYW
KSHLRGRPYHISALYVVDLNRFRALAAGDRLRGQYHTLLANLDQDLPNNM
QAMIPIKSLPQEWLWCETWCADEDLKTARTIDLCNNPLTKEPKLDRARRQ
VPEWTEYDNEIAELAVR
Ligand information
Ligand IDUDP
InChIInChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKeyXCCTYIAWTASOJW-XVFCMESISA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)OP(=O)(O)O)O)O
CACTVS 3.370O[CH]1[CH](O)[CH](O[CH]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
CACTVS 3.370O[C@H]1[C@@H](O)[C@@H](O[C@@H]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)O)O)O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC2OC(N1C(=O)NC(=O)C=C1)C(O)C2O
FormulaC9 H14 N2 O12 P2
NameURIDINE-5'-DIPHOSPHATE
ChEMBLCHEMBL130266
DrugBankDB03435
ZINCZINC000004490939
PDB chain5y7f Chain A Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5y7f Visualisation of a flexible modular structure of the ER folding-sensor enzyme UGGT.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		V1197 A1198 S1199 Y1203 I1271 D1294 A1295 D1296 C1429 N1430
Binding residue
(residue number reindexed from 1)		V8 A9 S10 Y14 I82 D105 A106 D107 C234 N235
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
GO:0046872 metal ion binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006486 protein glycosylation
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043934 sporulation
GO:0097359 UDP-glucosylation
Cellular Component
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5y7f, PDBe:5y7f, PDBj:5y7f
PDBsum5y7f
PubMed28939828
UniProtA0A2D0TCJ6

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