Structure of PDB 5xuu Chain A Binding Site BS01 |
| >5xuu Chain A (length=1213) Species: 1410628 (Lachnospiraceae bacterium ND2006)
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MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGV
KKLLDRYYLSFINDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEIN
LRKEIAKAFKGNEGYKSLFKKDIIETILPEFLDDKDEIALVNSFNGFTTA
FTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKH
EVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGE
KIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEV
LEVFRNTLNKNSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKD
IFGEWNVIRDKWNAEYDDIHLVTEKYEDDRRKSFKKIGSFSLEQLQEYAD
ADLSVVEKLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKNDAVVAI
MKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILLKVDHIYD
AIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYL
AIMDKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAY
YNPSEDIQKIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDF
NFSETEKYKDIAGFYREVEEQGYKVSFESASKKEVDKLVEEGKLYMFQIY
NKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFMRRASLKKEE
LVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKC
PKNIFKINTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVEQYS
LNEIINNFNGIRIKTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYIS
QVVHKICELVEKYDAVIALEDLNSGFKNSRVKVEKQVYQKFEKMLIDKLN
YMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFIFYIPAWLTSKID
PSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT
DADYIKKWKLYSYGNRIRIFRDWEEVCLTSAYKELFNKYGINYQQGDIRA
LLCEQSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYD
SRNYEAQENAILPKNADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAI
SNKEWLEYAQTSV |
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| PDB | 5xuu Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. |
| Resolution | 2.5 Å |
Binding residue
(original residue number in PDB) | S14 K15 T16 R18 F19 K20 K51 N157 R158 R174 L261 Q264 Y277 K278 V280 W355 K464 D505 R508 K520 N706 K707 S710 K712 H714 G715 T716 N718 H720 E743 R747 H759 I765 A766 N767 K768 N769 N772 K774 T777 L779 Y781 Y784 K785 D786 R788 Q793 H797 F863 Y872 F884 R887 E898 G902 S905 H909 K937 K953 K960 |
Binding residue
(residue number reindexed from 1) | S14 K15 T16 R18 F19 K20 K51 N157 R158 R174 L261 Q264 Y277 K278 V280 W355 K459 D500 R503 K515 N701 K702 S705 K707 H709 G710 T711 N713 H715 E738 R742 H754 I760 A761 N762 K763 N764 N767 K769 T772 L774 Y776 Y779 K780 D781 R783 Q788 H792 F858 Y867 F879 R882 E893 G897 S900 H904 K932 K948 K955 |
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| Enzyme Commision number |
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