Structure of PDB 5xsn Chain A Binding Site BS01

Receptor Information
>5xsn Chain A (length=333) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRARVISHALKDILAEGDKVIIMGHKRPDLDAIGAAIGVSRFAMMNNLEA
YIVLNETDIDPTLRRVMNEIDKKPELRERFITSDDAWDMMTSKTTVVIVD
THKPELVLDENVLNKANRKVVIDHHRRGESFISNPLLIYMEPYASSTAEL
VTELLEYQPTEQRLTRLESTVMYAGIIVDTRNFTLRTGSRTFDAASYLRA
HGADTILTQHFLKDDVDTYINRSELIRTVKVEDNGIAIAHGSDDKIYHPV
TVAQAADELLSLEGIEASYVVARREDNLIGISARSLGSVNVQLTMEALGG
GGHLTNAATQLKGVTVEEAIAQLQQAITEQLSR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5xsn Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5xsn Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase
Resolution2.501 Å
Binding residue
(original residue number in PDB)		D349 D418 H442 H443 D497
Binding residue
(residue number reindexed from 1)		D31 D100 H124 H125 D179
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.4.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:5xsn, PDBe:5xsn, PDBj:5xsn
PDBsum5xsn
PubMed29203646
UniProtA0A0U1MUE2

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