Structure of PDB 5xqz Chain A Binding Site BS01

Receptor Information
>5xqz Chain A (length=178) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEA
SCPVMSAGPRYEYHWADNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPS
KIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFK
HFIFFVQEFNLIDRRELAPLQELIEKLG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5xqz Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5xqz Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C79 C84 H161 H166
Binding residue
(residue number reindexed from 1)		C47 C52 H127 H132
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5xqz, PDBe:5xqz, PDBj:5xqz
PDBsum5xqz
PubMed28947795
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

[Back to BioLiP]