Structure of PDB 5xpg Chain A Binding Site BS01 |
| >5xpg Chain A (length=684) Species: 262724 (Thermus thermophilus HB27)
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NHLGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVAR
RAGGVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPK
DPGERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGA
VLDLWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRT
WELLRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPR
KPIPHLTGLLVPVLTLEDLHEEEGSLALSLPWEERRRRTREIASWIGRRL
GLGTPEAVRAQAYRLSIPKLMGRRAVSKPADALRVGFYRAQETALALLRL
DGAQGWPEFLRRALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEE
GVQAVLVLTPPMAWEDRNRLKALLLREGLPSQILNVPLREEERHRWENAL
LGLLAKAGLQVVALSGAYPAELAVGFDAGGRESFRFGGAACAVGGDGGHL
LWTLPEAQAGERIPQEVVWDLLEETLWAFRRKAGRLPSRVLLLRNGRVPQ
DEFALALEALAREGIAYDLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTF
LLLTVHRDFRGTPRPLKLVHEAGDTPLEALAHQIFHLTRLYPASGFAFPR
LPAPLHLADRLVKEVGRLGIRHLKEVDREKLFFV |
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| PDB | 5xpg Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. |
| Resolution | 2.8 Å |
Binding residue
(original residue number in PDB) | R39 V42 Y43 A170 Y171 R172 I173 R192 T201 S280 R286 M413 W415 K422 Q433 I434 N436 H445 R446 N449 K457 E512 R513 R580 D609 T613 R615 A644 S645 A648 R651 H657 R661 |
Binding residue
(residue number reindexed from 1) | R38 V41 Y42 A169 Y170 R171 I172 R191 T200 S279 R285 M412 W414 K421 Q432 I433 N435 H444 R445 N448 K456 E511 R512 R579 D608 T612 R614 A643 S644 A647 R650 H656 R660 |
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