Structure of PDB 5xp8 Chain A Binding Site BS01 |
| >5xp8 Chain A (length=678) Species: 262724 (Thermus thermophilus HB27)
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NHLGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVAR
RAGGVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPK
DPGERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGA
VLDLWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRT
WELLRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPR
KPIPHLTGLLVPVLTLEDLHALSLPWEERRRRTREIASWIGRRLGLGTPE
AVRAQAYRLSIPKLMGRRAVSKPADALRVGFYRAQETALALLRLDGAQGW
PEFLRRALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEEGVQAVL
VLTPPMAWEDRNRLKALLLREGLPSQILNVPLREEERHRWENALLGLLAK
AGLQVVALSGAYPAELAVGFDAGGRESFRFGGAACAVGGDGGHLLWTLPE
AQAGERIPQEVVWDLLEETLWAFRRKAGRLPSRVLLLRDGRVPQDEFALA
LEALAREGIAYDLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTFLLLTVH
RDFRGTPRPLKLVHEAGDTPLEALAHQIFHLTRLYPASGFAFPRLPAPLH
LADRLVKEVGRLGIRHLKEVDREKLFFV |
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| PDB | 5xp8 Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. |
| Resolution | 3.1 Å |
Binding residue
(original residue number in PDB) | Y43 A170 Y171 R172 I173 T201 L265 L267 R286 M413 W415 K422 Q433 I434 L435 N436 H445 R446 N449 K457 E512 R513 R580 V606 R611 T613 P614 R615 S645 F647 A648 P650 R651 R661 V685 |
Binding residue
(residue number reindexed from 1) | Y42 A169 Y170 R171 I172 T200 L264 L266 R279 M406 W408 K415 Q426 I427 L428 N429 H438 R439 N442 K450 E505 R506 R573 V599 R604 T606 P607 R608 S638 F640 A641 P643 R644 R654 V678 |
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