Structure of PDB 5xow Chain A Binding Site BS01 |
| >5xow Chain A (length=684) Species: 262724 (Thermus thermophilus HB27)
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NHLGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVAR
RAGGVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPK
DPGERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGA
VLDLWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRT
WELLRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPR
KPIPHLTGLLVPVLTLEDLHEEEGSLALSLPWEERRRRTREIASWIGRRL
GLGTPEAVRAQAYRLSIPKLMGRRAVSKPADALRVGFYRAQETALALLRL
DGAQGWPEFLRRALLRAFGASGASLRLHTLHAHPSQGLAFREALRKAKEE
GVQAVLVLTPPMAWEDRNRLKALLLREGLPSQILNVPLREEERHRWENAL
LGLLAKAGLQVVALSGAYPAELAVGFDAGGRESFRFGGAACAVGGDGGHL
LWTLPEAQAGERIPQEVVWDLLEETLWAFRRKAGRLPSRVLLLRNGRVPQ
DEFALALEALAREGIAYDLVSVRKSGGGRVYPVQGRLADGLYVPLEDKTF
LLLTVHRDFRGTPRPLKLVHEAGDTPLEALAHQIFHLTRLYPASGFAFPR
LPAPLHLADRLVKEVGRLGIRHLKEVDREKLFFV |
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| PDB | 5xow Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes |
| Resolution | 2.902 Å |
Binding residue
(original residue number in PDB) | R39 E40 V42 Y43 A170 Y171 R172 I173 R192 L279 S280 L281 R286 W415 K422 Q433 I434 N436 H445 R446 N449 K457 E512 R513 P550 R580 D609 T613 R615 A644 P650 R651 H657 R661 V685 |
Binding residue
(residue number reindexed from 1) | R38 E39 V41 Y42 A169 Y170 R171 I172 R191 L278 S279 L280 R285 W414 K421 Q432 I433 N435 H444 R445 N448 K456 E511 R512 P549 R579 D608 T612 R614 A643 P649 R650 H656 R660 V684 |
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