Structure of PDB 5xad Chain A Binding Site BS01

Receptor Information
>5xad Chain A (length=117) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTK
FLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYES
EKDEDGFLYMVYASQET
Ligand information
>5xad Chain C (length=24) Species: 91891 (Legionella pneumophila subsp. pneumophila) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SIVDEFEELGEQESDIDEFDLLEG
Receptor-Ligand Complex Structure
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PDB5xad A novel conformation of the LC3-interacting region motif revealed by the structure of a complex between LC3B and RavZ
Resolution1.88 Å
Binding residue
(original residue number in PDB)		P2 S3 R10
Binding residue
(residue number reindexed from 1)		P1 S2 R9
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008429 phosphatidylethanolamine binding
GO:0031625 ubiquitin protein ligase binding
GO:0097001 ceramide binding
Biological Process
GO:0000045 autophagosome assembly
GO:0000422 autophagy of mitochondrion
GO:0000423 mitophagy
GO:0006914 autophagy
GO:0006995 cellular response to nitrogen starvation
GO:0009267 cellular response to starvation
GO:0016236 macroautophagy
GO:0097352 autophagosome maturation
Cellular Component
GO:0000421 autophagosome membrane
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005776 autophagosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005930 axoneme
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0031090 organelle membrane
GO:0031410 cytoplasmic vesicle
GO:0031966 mitochondrial membrane
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5xad, PDBe:5xad, PDBj:5xad
PDBsum5xad
PubMed28668392
UniProtQ9GZQ8|MLP3B_HUMAN Microtubule-associated proteins 1A/1B light chain 3B (Gene Name=MAP1LC3B)

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