Structure of PDB 5x4i Chain A Binding Site BS01

Receptor Information
>5x4i Chain A (length=470) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMDKEGFLNKVREAVDVVKLHIELGHTIRIISHRDADGITSAAILAKALG
REGASFHISIVKQVSEDLLRELKDEDYKIFIFSALGSGSLSLIKEYLKEK
TVIILDHHPPENVKLEEKHILVNPVQFGANSVRDLSGSGVTYFFARELNE
KNRDLAYIAIVGAVGDMQENDGVFHGMNLDIIEDGKSLGILEVKKELRLF
GRETRPLYQMLAYATNPEIPEVTGDERKAIEWLKNKGFNPEKKYWELSEE
EKKKLHDFLIIHMIKHGAGKEDIDRLIGDVVISPLYPEGDPRHEAREFAT
LLNATGRLNLGNLGVAVCLGDEEAFRKALKMVEDYKREQIEARKWLLQNW
NSEVWEGDHVYVLYVGKSIRDTLVGIAASMAINAGLADPEKPVIVFADTD
EDPNLLKGSARTTERALAKGYNLGEALRKAAELVNGEGGGHAIAAGIRIP
RARLAEFRKLIDKILGEQVS
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5x4i Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5x4i The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45.
Resolution2.092 Å
Binding residue
(original residue number in PDB)		D36 H106 D165
Binding residue
(residue number reindexed from 1)		D37 H107 D166
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5x4i, PDBe:5x4i, PDBj:5x4i
PDBsum5x4i
PubMed30053256
UniProtQ8TZE0

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