Structure of PDB 5x2q Chain A Binding Site BS01

Receptor Information

>5x2q Chain A (length=421) Species: 8090 (Oryzias latipes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SEFHLRGDYLIGGLFNIHYVAAANFQRPQAIDCSSKLFILPNYRRFQMMR
FSVEEINNSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPWED
PNAIGVVGPFTSTHALSIAPIFMTNLFPMVSYGCSGSVFSKENLYPSFLR
TVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSEI
CLAFYKAINVNTDYLQVFKQIEEQNIKVIVVFAPKVYAEAVVESAVQLNV
TNKVWIADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFIYSAI
FCNQKCNCSNLSVKSLLNADPSFSFPVYAAVYAIAHALHNTLRCGSDRCP
KNITVHPHMILEELKKSNFTLLNQTVQFDENGDPKFGSLSVVFWNSSGNA
EEVGSYHFQSLSINKTKIKWF

Ligand information

Ligand ID

GLY

InChI

InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 1.5.0	C(C(=O)O)N
CACTVS 3.341	NCC(O)=O
ACDLabs 10.04	O=C(O)CN

Formula

C2 H5 N O2

Name

GLYCINE

PDB chain

5x2q Chain A Residue 951 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5x2q Structural basis for perception of diverse chemical substances by T1r taste receptors
Resolution	2.6 Å
Binding residue (original residue number in PDB)	T141 S142 G163 S165 F213
Binding residue (residue number reindexed from 1)	T111 S112 G133 S135 F183
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004930	G protein-coupled receptor activity

	Biological Process
GO:0007186	G protein-coupled receptor signaling pathway

	Cellular Component
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:5x2q, PDBe:5x2q, PDBj:5x2q
PDBsum	5x2q
PubMed	28534491
UniProt	A0A173M0G2

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