Structure of PDB 5x2h Chain A Binding Site BS01 |
| >5x2h Chain A (length=746) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819)
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MARILAFDIGISSIGWAFSENDELKDCGVRIFTESLALPRRLARSARKRL
ARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRA
LNELLSKQDFARVILHIAKRRGYDDIKNKEKGAILKAIKQNEEKLANYQS
VGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFKKQ
REFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNSPL
AFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKK
LLGLSDDYEFKGEKGTYFIEFKKYKEFISQDDLNEIAKDITLIKDEIKLK
KALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLVTPLMLEGKKYDEACN
ELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALLKK
YGKVHKINIELGGYIARLVLNYTKDYLDFLPLSDVHVEAKSGMLTSALRH
TWGFSAKDRNNHLHHAIDAVIIAYRQKVLDKIDEIFVSKPERKKPSGALH
EETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKH
KKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSL
YKDSLILIQTKDMQEPEFVYYNAFTSSTVSLIVSKHDNKFETLSKNQKIL
FKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKK |
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| PDB | 5x2h Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems |
| Resolution | 2.3 Å |
Binding residue
(original residue number in PDB) | S43 L44 A45 R48 R49 A51 R52 R55 K56 R57 L58 R60 R61 K62 A63 N66 H67 K69 H70 N74 S85 L90 Y94 G96 S97 P101 Y102 H124 K127 R128 R129 G130 Y131 Q172 E180 F181 V184 R185 N186 K187 K233 R234 A235 L236 K237 S247 K257 F265 V266 L394 N395 Y414 T448 N449 P450 R454 K457 R460 K461 R645 E779 R780 K781 K782 P783 S784 G785 A786 L787 H788 F792 N821 K823 F854 A855 I964 S966 K973 A974 E975 E980 D981 F982 |
Binding residue
(residue number reindexed from 1) | S35 L36 A37 R40 R41 A43 R44 R47 K48 R49 L50 R52 R53 K54 A55 N58 H59 K61 H62 N66 S77 L82 Y86 G88 S89 P93 Y94 H116 K119 R120 R121 G122 Y123 Q161 E169 F170 V173 R174 N175 K176 K222 R223 A224 L225 K226 S236 K246 F254 V255 L375 N376 Y395 T429 N430 P431 R435 K438 R441 K442 R467 E541 R542 K543 K544 P545 S546 G547 A548 L549 H550 F554 N583 K585 F616 A617 I726 S728 K735 A736 E737 E742 D743 F744 |
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