Structure of PDB 5wzj Chain A Binding Site BS01

Receptor Information
>5wzj Chain A (length=534) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDPETSKYFSEIANLFDSNEVELEERSVICGNALEETRGREYEIATDYII
SHVLQTLLEGCELDQLCSFIRNSASVFPAIAMDRSGSHVAESALKSLATH
LENPDAYSVIEEALHSICKVIVDNPLDMMCNCYGSHVLRRLLCLCKGVSL
DSPELYGAKSSKALAKRLNLPHQGFPGMLTYLLSGLLSCSREDMKYLQVD
QYSSLVLQTALRLMLKQDEQLLEIIPLILRCNGFHIETNVAKEILESMKD
NSFSHLVEVILEVAPESLYNEMFNKVFKNSLFELSVDRCANFVIQALISH
ARDQEQMGIMWEELAPRFKDLLEQGKSGVVASLIAVSQRLQSHENKCCEA
LVGAVCSTNESRISILPRLLFLDYYFGCRDKSTWEWAPGAKMHVMGCLIL
QGIFKFSSDHIQPYITSLTSMKAEYITETAKDSSGARVIEAFLASDAATK
QKRRLIIKLRGHFGELSLHTSGSFTVEKCFDACNLTLREAIASELLDVKV
DLSKTKQGPYLLRKLDIDGYASRPDQWKSRQEAK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5wzj Structural basis for the specific recognition of 18S rRNA by APUM23.
Resolution2.101 Å
Binding residue
(original residue number in PDB)		S138 H139 Q142 R171 S174 H175 E178 Y220 H223 R226 Y243 G244 K246 S248 L251 R254 Q300 L304 Q307 N357 S360 H361 E364 R394 C395 N397 F398 Q401 G431 K432 G434 M501 Q507 S539 S540 R543 E546 S577 S579 F580 E583 Q613 Y616
Binding residue
(residue number reindexed from 1)		S51 H52 Q55 R84 S87 H88 E91 Y133 H136 R139 Y156 G157 K159 S161 L164 R167 Q201 L205 Q208 N251 S254 H255 E258 R288 C289 N291 F292 Q295 G325 K326 G328 M395 Q401 S433 S434 R437 E440 S471 S473 F474 E477 Q507 Y510
Binding affinityPDBbind-CN: Kd=13nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:5wzj, PDBe:5wzj, PDBj:5wzj
PDBsum5wzj
PubMed29036323
UniProtQ9C552|PUM23_ARATH Pumilio homolog 23 (Gene Name=APUM23)

[Back to BioLiP]