Structure of PDB 5wzh Chain A Binding Site BS01

Receptor Information
>5wzh Chain A (length=533) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDPETSKYFSEIANLFDSNEVELEERSVICGNALEETRGREYEIATDYII
SHVLQTLLEGCELDQLCSFIRNSASVFPAIAMDRSGSHVAESALKSLATH
LENPDAYSVIEEALHSICKVIVDNPLDMMCNCYGSHVLRRLLCLCKGVSL
DSPELYGAKSSKALAKRLNLHQGFPGMLTYLLSGLLSCSREDMKYLQVDQ
YSSLVLQTALRLMLKQDEQLLEIIPLILRCNGFHIETNVAKEILESMKDN
SFSHLVEVILEVAPESLYNEMFNKVFKNSLFELSVDRCANFVIQALISHA
RDQEQMGIMWEELAPRFKDLLEQGKSGVVASLIAVSQRLQSHENKCCEAL
VGAVCSTNESRISILPRLLFLDYYFGCRDKSTWEWAPGAKMHVMGCLILQ
GIFKFSSDHIQPYITSLTSMKAEYITETAKDSSGARVIEAFLASDAATKQ
KRRLIIKLRGHFGELSLHTSGSFTVEKCFDACNLTLREAIASELLDVKVD
LSKTKQGPYLLRKLDIDGYASRPDQWKSRQEAK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5wzh Structural basis for the specific recognition of 18S rRNA by APUM23.
Resolution2.509 Å
Binding residue
(original residue number in PDB)		S138 H139 Q142 R171 S174 H175 E178 Y220 H223 R226 Y243 G244 S248 L251 R254 Q300 Y301 L304 Q307 N357 S360 H361 E364 R394 N397 F398 Q401 G431 K432 G434 M501 L504 Q507 S539 S540 R543 E546 S577 S579 F580 E583 Y616
Binding residue
(residue number reindexed from 1)		S51 H52 Q55 R84 S87 H88 E91 Y133 H136 R139 Y156 G157 S161 L164 R167 Q200 Y201 L204 Q207 N250 S253 H254 E257 R287 N290 F291 Q294 G324 K325 G327 M394 L397 Q400 S432 S433 R436 E439 S470 S472 F473 E476 Y509
Binding affinityPDBbind-CN: Kd=21nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:5wzh, PDBe:5wzh, PDBj:5wzh
PDBsum5wzh
PubMed29036323
UniProtQ9C552|PUM23_ARATH Pumilio homolog 23 (Gene Name=APUM23)

[Back to BioLiP]