Structure of PDB 5wxd Chain A Binding Site BS01

Receptor Information
>5wxd Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFG
CDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAA
HVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
>5wxd Chain E (length=11) Species: 1774282 (Influenza A virus (A/chicken/China/028/2014(H7N9))) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LYKKLKREMTF
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5wxd Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.
Resolution3.295 Å
Binding residue
(original residue number in PDB)		Y7 E63 K66 H70 T73 N77 I80 Y84 M97 F99 Y123 T143 K146 W147 Y159 Y171
Binding residue
(residue number reindexed from 1)		Y7 E63 K66 H70 T73 N77 I80 Y84 M97 F99 Y123 T143 K146 W147 Y159 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5wxd, PDBe:5wxd, PDBj:5wxd
PDBsum5wxd
PubMed30087171
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

[Back to BioLiP]