Structure of PDB 5wni Chain A Binding Site BS01

Receptor Information

>5wni Chain A (length=263) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

WALGLLRTFDAGEFAGWEKVGSQVYKVRHVHWKTWLAIKCSPSLHVDDRE
RMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEP
LPWDLRFRIVHETAVGMNFLHCMSPPLLHLNLKPANILLDAHYHVKISDF
GLAKCNFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFAD
EKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPT
FQEITSETEDLCE

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

5wni Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5wni Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
Resolution	2.65 Å
Binding residue (original residue number in PDB)	N148 D161
Binding residue (residue number reindexed from 1)	N136 D149
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	N143 A147 N148 D161
Catalytic site (residue number reindexed from 1)	N131 A135 N136 D149
Enzyme Commision number	2.7.11.1: non-specific serine/threonine protein kinase.

Gene Ontology

	Molecular Function
GO:0004672	protein kinase activity
GO:0005524	ATP binding

	Biological Process
GO:0006468	protein phosphorylation

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Molecular Function

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Biological Process

External links

PDB	RCSB:5wni, PDBe:5wni, PDBj:5wni
PDBsum	5wni
PubMed	29706531
UniProt	Q9ERK0\|RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 (Gene Name=Ripk4)

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