Structure of PDB 5wm8 Chain A Binding Site BS01
Receptor Information
>5wm8 Chain A (length=432) Species:
559292
(Saccharomyces cerevisiae S288C) [
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IVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKDTY
IIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCNYV
ARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRLN
IFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCTV
SIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHS
TLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEE
SLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNE
INKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGI
IATEMKSLYRTLGCPPMELRGLALQFNKLVDV
Ligand information
>5wm8 Chain P (length=12) [
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ggggtgtggtag
Receptor-Ligand Complex Structure
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PDB
5wm8
Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.
Resolution
1.92 Å
Binding residue
(original residue number in PDB)
I464 G552 G554 H555 S556 T557 S692 R693 S694 R696
Binding residue
(residue number reindexed from 1)
I158 G246 G248 H249 S250 T251 S386 R387 S388 R390
Enzymatic activity
Enzyme Commision number
2.7.7.-
Gene Ontology
Molecular Function
GO:0003684
damaged DNA binding
GO:0003887
DNA-directed DNA polymerase activity
Biological Process
GO:0006281
DNA repair
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Molecular Function
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Biological Process
External links
PDB
RCSB:5wm8
,
PDBe:5wm8
,
PDBj:5wm8
PDBsum
5wm8
PubMed
29042535
UniProt
P12689
|REV1_YEAST DNA repair protein REV1 (Gene Name=REV1)
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