Structure of PDB 5wgd Chain A Binding Site BS01
Receptor Information
>5wgd Chain A (length=228) Species:
9606
(Homo sapiens) [
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LSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVVPLSDLLLEMLDAH
Ligand information
>5wgd Chain E (length=11) Species:
32630
(synthetic construct) [
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HKILHKLLQDS
Receptor-Ligand Complex Structure
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PDB
5wgd
A "cross-stitched" peptide with improved helicity and proteolytic stability.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
I358 L372 V376 E380 E542
Binding residue
(residue number reindexed from 1)
I51 L65 V69 E73 E223
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5wgd
,
PDBe:5wgd
,
PDBj:5wgd
PDBsum
5wgd
PubMed
29725689
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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