Structure of PDB 5wg1 Chain A Binding Site BS01
Receptor Information
>5wg1 Chain A (length=280) Species:
9606
(Homo sapiens) [
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TAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGG
RNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVG
GSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFD
GTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQD
QLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLD
SVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
>5wg1 Chain P (length=9) Species:
9606
(Homo sapiens) [
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LDEEAGEFL
Receptor-Ligand Complex Structure
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PDB
5wg1
Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2).
Resolution
2.021 Å
Binding residue
(original residue number in PDB)
Y334 S363 R380 N382 R415 S508 G509 Y525 S555 A556 Y572 F577 S602
Binding residue
(residue number reindexed from 1)
Y5 S34 R51 N53 R86 S179 G180 Y196 S226 A227 Y243 F248 S273
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5wg1
,
PDBe:5wg1
,
PDBj:5wg1
PDBsum
5wg1
PubMed
31851823
UniProt
Q14145
|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)
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