Structure of PDB 5wfv Chain A Binding Site BS01
Receptor Information
>5wfv Chain A (length=284) Species:
9606
(Homo sapiens) [
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RLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLY
AVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHI
YAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAV
GGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGY
DGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGH
TFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
>5wfv Chain P (length=9) Species:
9606
(Homo sapiens) [
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LDEETGEFL
Receptor-Ligand Complex Structure
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PDB
5wfv
Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2).
Resolution
1.91 Å
Binding residue
(original residue number in PDB)
Y334 S363 R380 N382 R415 R483 S508 G509 Y525 S555 Y572 F577 S602
Binding residue
(residue number reindexed from 1)
Y9 S38 R55 N57 R90 R158 S183 G184 Y200 S230 Y247 F252 S277
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5wfv
,
PDBe:5wfv
,
PDBj:5wfv
PDBsum
5wfv
PubMed
31851823
UniProt
Q14145
|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)
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