Structure of PDB 5weu Chain A Binding Site BS01

Receptor Information
>5weu Chain A (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARW
IEQEGPEYWERETRRAKGNEQCFRVDLRTALRYYNQSAGGSHTLQWMAGC
DVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAG
AAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTL
RCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPL
GKEQKYTCHVEHEGLPEPLTLRW
Ligand information
>5weu Chain P (length=10) Species: 11686 (Human immunodeficiency virus type 1 (BRU ISOLATE)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RGPGCAFVTI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5weu Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Resolution1.584 Å
Binding residue
(original residue number in PDB)
Y7 R62 E63 R66 N70 C73 D77 Y84 W97 W114 T143 K146 W147 R155 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 R61 E62 R65 N69 C72 D76 Y83 W96 W113 T142 K145 W146 R154 Y158 E162 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5weu, PDBe:5weu, PDBj:5weu
PDBsum5weu
PubMed29025991
UniProtP01900|HA12_MOUSE H-2 class I histocompatibility antigen, D-D alpha chain (Gene Name=H2-D1)

[Back to BioLiP]