Structure of PDB 5wes Chain A Binding Site BS01

Receptor Information
>5wes Chain A (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARW
IEQEGPEYWERETRRAKGNEQCFRVDLRTALRYYNQSAGGSHTLQWMAGC
DVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAG
AAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTL
RCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPL
GKEQKYTCHVEHEGLPEPLTLRW
Ligand information
>5wes Chain P (length=5) Species: 11686 (Human immunodeficiency virus type 1 (BRU ISOLATE)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RGPGC
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wes Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Resolution2.706 Å
Binding residue
(original residue number in PDB)
Y7 R62 E63 R66 N70 C73 W97 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 R61 E62 R65 N69 C72 W96 Y158 E162 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5wes, PDBe:5wes, PDBj:5wes
PDBsum5wes
PubMed29025991
UniProtP01900|HA12_MOUSE H-2 class I histocompatibility antigen, D-D alpha chain (Gene Name=H2-D1)

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