Structure of PDB 5w7x Chain A Binding Site BS01
Receptor Information
>5w7x Chain A (length=101) Species:
9606
(Homo sapiens) [
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GGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQL
RIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILS
I
Ligand information
>5w7x Chain E (length=8) Species:
9606
(Homo sapiens) [
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PYAGSTDE
Receptor-Ligand Complex Structure
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PDB
5w7x
Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Resolution
2.005 Å
Binding residue
(original residue number in PDB)
R27 G28 P29 I33 T34 K36 V38 S39 R40 H58
Binding residue
(residue number reindexed from 1)
R25 G26 P27 I31 T32 K34 V36 S37 R38 H56
Enzymatic activity
Enzyme Commision number
3.1.-.-
Gene Ontology
Molecular Function
GO:0003906
DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0008408
3'-5' exonuclease activity
Biological Process
GO:0006302
double-strand break repair
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Molecular Function
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Biological Process
External links
PDB
RCSB:5w7x
,
PDBe:5w7x
,
PDBj:5w7x
PDBsum
5w7x
PubMed
29059378
UniProt
Q8IW19
|APLF_HUMAN Aprataxin and PNK-like factor (Gene Name=APLF)
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