Structure of PDB 5w6t Chain A Binding Site BS01

Receptor Information

>5w6t Chain A (length=322) Species: 211044 (Influenza A virus (A/Puerto Rico/8/1934(H1N1))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPL
QLGKCNIAGWLLGNPECDPLLPVRSWSYIVETPNSENGICYPGDFIDYEE
LREQLSSVSSFERFEIFPKESSWPNHNTNGVTAACSHEGKSSFYRNLLWL
TEKEGSYPKLKNSYVNKKGKEVLVLWGIHHPPNSKEQQNLYQNENAYVSV
VTSNYNRRFTPEIAERPKVRDQAGRMNYYWTLLKPGDTIIFEANGNLIAP
MYAFALSRGFGSGIITSNASMHECNTKCQTPLGAINSSLPYQNIHPVTIG
ECPKYVRSAKLRMVTGLRNIPS

Ligand information

>5w6t Chain F (length=11) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

FPLEYFEWLSA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5w6t Potent peptidic fusion inhibitors of influenza virus.
Resolution	2.59 Å
Binding residue (original residue number in PDB)	H18 H38 V40 T318
Binding residue (residue number reindexed from 1)	H8 H28 V30 T315

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0046789	host cell surface receptor binding

	Biological Process
GO:0019064	fusion of virus membrane with host plasma membrane

	Cellular Component
GO:0019031	viral envelope

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Molecular Function

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Cellular Component

External links

PDB	RCSB:5w6t, PDBe:5w6t, PDBj:5w6t
PDBsum	5w6t
PubMed	28971971
UniProt	P03452\|HEMA_I34A1 Hemagglutinin (Gene Name=HA)

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