Structure of PDB 5w45 Chain A Binding Site BS01

Receptor Information
>5w45 Chain A (length=181) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALLTAETFRLQFNNKRRLRRPYYPRKALLCYQLTPQNGSTPTRGYFENKK
KCHAAICFINEIKSMGLDETQCYQVTCYLTWSPCSSCASELVDFIKAHDH
LNLRIFASRLYYHASKPQQDGLRLLSQEGVPVEVMGFPEFADCWENFVDH
EKPASFNPYKMLEELDKNSRAIKRRLDRIKS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5w45 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5w45 Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H.
Resolution2.486 Å
Binding residue
(original residue number in PDB)		H54 C88
Binding residue
(residue number reindexed from 1)		H53 C87
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.4.38: single-stranded DNA cytosine deaminase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:5w45, PDBe:5w45, PDBj:5w45
PDBsum5w45
PubMed29491387
UniProtQ6NTF7|ABC3H_HUMAN DNA dC->dU-editing enzyme APOBEC-3H (Gene Name=APOBEC3H)

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