Structure of PDB 5w36 Chain A Binding Site BS01

Receptor Information
>5w36 Chain A (length=321) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHMGSRSRLLAANAAAAAFYAQALQSDEAAPARQYLTERSFDAAAARKFG
CGFAPSGWDSLTKHLQRKGFEFEELEAAGLSRQGRHGPMDRFHRRLLWPI
RTSAGEVVGFGARRLFDDDAMEAKYVNTPETLLYKKSSVMFGIDLAKRDI
AKGHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGGEHLAMLRRLMMDDS
FFRGELIYVFDGDEAGRAAALKAFDGEQKLAGQSFVAVAPDGMDPCDLRL
KCGDAALRDLVARRTPLFEFAIRAAIAEMDLDSAEGRVAALRRCVPMVGQ
IKDPTLRDEYARQLAGWVGWA
Ligand information
Receptor-Ligand Complex Structure
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PDB5w36 Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.
Resolution2.46 Å
Binding residue
(original residue number in PDB)
Y143 R147 R221 K232 Y233
Binding residue
(residue number reindexed from 1)
Y35 R39 R113 K124 Y125
Enzymatic activity
Enzyme Commision number 2.7.7.101: DNA primase DnaG.
Gene Ontology
Molecular Function
GO:0016779 nucleotidyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:5w36, PDBe:5w36, PDBj:5w36
PDBsum5w36
PubMed29558114
UniProtP9WNW1|DNAG_MYCTU DNA primase (Gene Name=dnaG)

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