Structure of PDB 5w34 Chain A Binding Site BS01

Receptor Information
>5w34 Chain A (length=317) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSRSRLLAANAAAAAFYAQALQSDEAAPARQYLTERSFDAAAARKFGCG
FAPSGWDSLTKHLQRKGFEFEELEAAGLSRQGRHGPMDRFHRRLLWPIRT
SAGEVVGFGARRLFDDDAMEAKYVNTPETLLYKKSSVMFGIDLAKRDIAK
GHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGGEHLAMLRRLMMDFFRG
ELIYVFDGDEAGRAAALKAFDGEQKLAGQSFVAVAPDGMDPCDLRLKCGD
AALRDLVARRTPLFEFAIRAAIAEMDLDSAEGRVAALRRCVPMVGQIKDP
TLRDEYARQLAGWVGWA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w34 Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		G192 R193
Binding residue
(residue number reindexed from 1)		G82 R83
Binding affinityPDBbind-CN: Kd=0.5uM
Enzymatic activity
Enzyme Commision number 2.7.7.101: DNA primase DnaG.
Gene Ontology
Molecular Function
GO:0016779 nucleotidyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:5w34, PDBe:5w34, PDBj:5w34
PDBsum5w34
PubMed29558114
UniProtP9WNW1|DNAG_MYCTU DNA primase (Gene Name=dnaG)

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