Structure of PDB 5w1w Chain A Binding Site BS01
Receptor Information
>5w1w Chain A (length=272) Species:
9606
(Homo sapiens) [
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SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQGHTQDTELVETRPAGDGTFQKWAAVVVPSGEE
QRYTCHVQHEGLPEPVTLRWKP
Ligand information
>5w1w Chain C (length=9) Species:
9606
(Homo sapiens) [
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VMAPRTLVL
Receptor-Ligand Complex Structure
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PDB
5w1w
A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
Y7 H9 E63 S66 A67 I73 N77 T80 Y84 W97 H99 F116 W133 S143 K146 S147 E152 H155 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 H8 E62 S65 A66 I72 N76 T79 Y83 W96 H98 F115 W132 S142 K145 S146 E151 H154 Q155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5w1w
,
PDBe:5w1w
,
PDBj:5w1w
PDBsum
5w1w
PubMed
28972140
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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