Structure of PDB 5w0o Chain A Binding Site BS01

Receptor Information
>5w0o Chain A (length=338) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQD
FPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKH
SGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAI
DPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIP
VLQEIPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYT
EEFDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTN
FIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w0o Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Resolution2.488 Å
Binding residue
(original residue number in PDB)		I1099 A1102 K1103 V1104 N1124 A1163 S1164
Binding residue
(residue number reindexed from 1)		I109 A112 K113 V114 N134 A173 S174
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5w0o, PDBe:5w0o, PDBj:5w0o
PDBsum5w0o
PubMed28671666
UniProtQ5VYS8|TUT7_HUMAN Terminal uridylyltransferase 7 (Gene Name=TUT7)

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