Structure of PDB 5vyd Chain A Binding Site BS01

Receptor Information
>5vyd Chain A (length=314) Species: 946362 (Salpingoeca rosetta) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAASSLFTWDFDALDKSDEDLTAVCVRVFQELHVIEQFNIDEKKLRKWLQ
KVRTQYNKNPFHNWRHAVMVLHTTYLLLTSVATEFITEVELLAMLIAALS
HDLDHNGLTNAFHINSRSELALVYNDQSVLENHHSHLAFEILLEKGCNVV
ENLDEDEFKRLRAVIINCILNTDMATHHTKLSKMEEVNRLGGFINLAENN
DQRLFVLAVLLHTADLHNPIKPFESNKRWSARLQKEFNNQVELEAKMNLP
SLPFMRGNDEESLAKGEIGFINFVVKPWHQQLSQAFPKLDFLLDTIDANL
AEWKAIAESYRQMH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5vyd Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vyd Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetic Tool from the Choanoflagellate Salpingoeca rosetta.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H87 H122 D123 D236
Binding residue
(residue number reindexed from 1)		H66 H101 D102 D215
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.4.-
Gene Ontology
Molecular Function
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0008081 phosphoric diester hydrolase activity
Biological Process
GO:0007165 signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:5vyd, PDBe:5vyd, PDBj:5vyd
PDBsum5vyd
PubMed28976747
UniProtF2TZN0

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