Structure of PDB 5vvu Chain A Binding Site BS01

Receptor Information
>5vvu Chain A (length=424) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKYSPQMALKLALTEWLQEFGVPHQYS
VTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVIEEWRSRAAK
FEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGC
RSWAFRGGLAGEFQRLLPIDGAND
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vvu Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
N175 Y219 F223
Binding residue
(residue number reindexed from 1)
N117 Y161 F165
Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
External links
PDB RCSB:5vvu, PDBe:5vvu, PDBj:5vvu
PDBsum5vvu
PubMed28939839
UniProtO60502|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)

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