Structure of PDB 5vvt Chain A Binding Site BS01
Receptor Information
>5vvt Chain A (length=419) Species:
9606
(Homo sapiens) [
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HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKYSPQMALKLALTEWLQEFGVPHQYS
VTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSIEEWRSRAAKFEE
MCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCWAF
RGGLAGEFQRLLPIDGAND
Ligand information
>5vvt Chain B (length=2) Species:
9606
(Homo sapiens) [
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TL
Receptor-Ligand Complex Structure
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PDB
5vvt
Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
Y69 N175 Y219 V254
Binding residue
(residue number reindexed from 1)
Y11 N117 Y161 V196
Enzymatic activity
Enzyme Commision number
3.2.1.169
: protein O-GlcNAcase.
External links
PDB
RCSB:5vvt
,
PDBe:5vvt
,
PDBj:5vvt
PDBsum
5vvt
PubMed
28939839
UniProt
O60502
|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)
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