Structure of PDB 5vtp Chain A Binding Site BS01

Receptor Information
>5vtp Chain A (length=510) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKED
PVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKGE
DFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDLV
ERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGNY
DINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGIR
DSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCGK
FEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFLDAK
VKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMMSNK
NLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSISLKT
KSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPLTKL
SMTITNFDII
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5vtp Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vtp The C-terminal region of translesion synthesis DNA polymerase eta is partially unstructured and has high conformational flexibility.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D30 E156
Binding residue
(residue number reindexed from 1)		D31 E157
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5vtp, PDBe:5vtp, PDBj:5vtp
PDBsum5vtp
PubMed29385534
UniProtQ04049|POLH_YEAST DNA polymerase eta (Gene Name=RAD30)

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