Structure of PDB 5vt8 Chain A Binding Site BS01

Receptor Information
>5vt8 Chain A (length=208) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDSQLTYSLEGPGMEAFS
VDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDN
RPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTG
NRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQP
LQVALEDI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5vt8 Chain A Residue 2801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vt8 Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		E2497 D2580 V2581 D2583 D2618
Binding residue
(residue number reindexed from 1)		E17 D96 V97 D99 D134
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vt8, PDBe:5vt8, PDBj:5vt8
PDBsum5vt8
PubMed30033219
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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