Structure of PDB 5vsl Chain A Binding Site BS01
Receptor Information
>5vsl Chain A (length=262) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
TPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKI
NFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYG
EYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKI
NSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFL
ISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTDPSKSI
LDVGVEEAIKFS
Ligand information
Ligand ID
SF4
InChI
InChI=1S/4Fe.4S
InChIKey
LJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
Software
SMILES
OpenEye OEToolkits 2.0.7
[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385
S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
Formula
Fe4 S4
Name
IRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain
5vsl Chain A Residue 401 [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5vsl
Structural studies of viperin, an antiviral radical SAM enzyme.
Resolution
1.972 Å
Binding residue
(original residue number in PDB)
C84 Y86 C88 C91 G126 N158 R194
Binding residue
(residue number reindexed from 1)
C13 Y15 C17 C20 G55 N87 R123
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
C84 C88 C91
Catalytic site (residue number reindexed from 1)
C13 C17 C20
Enzyme Commision number
4.2.-.-
Gene Ontology
Molecular Function
GO:0003824
catalytic activity
GO:0051536
iron-sulfur cluster binding
Biological Process
GO:0051607
defense response to virus
Cellular Component
GO:0005789
endoplasmic reticulum membrane
GO:0005811
lipid droplet
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:5vsl
,
PDBe:5vsl
,
PDBj:5vsl
PDBsum
5vsl
PubMed
28607080
UniProt
Q8CBB9
|RSAD2_MOUSE S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (Gene Name=Rsad2)
[
Back to BioLiP
]