Structure of PDB 5vpl Chain A Binding Site BS01

Receptor Information
>5vpl Chain A (length=223) Species: 6954 (Dermatophagoides farinae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSACRINSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLA
YRNTSLDLSEQELVDCASQHGCHGDTIPRGIEYIQQNGVVEERSYPYVAR
EQQCRRPNSQHYGISNYCQIYPPDVKQIREALTQTHTAIAVIIGIKDLRA
FQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGVDYWIVRNSWDTTWGDS
GYGYFQAGNNLMMIEQYPYVVIM
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5vpl Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5vpl Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D57 L58 E60 E92
Binding residue
(residue number reindexed from 1)		D57 L58 E60 E92
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) Q29 C35 H171 N191
Catalytic site (residue number reindexed from 1) Q29 C35 H171 N191
Enzyme Commision number 3.4.22.65: peptidase 1 (mite).
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5vpl, PDBe:5vpl, PDBj:5vpl
PDBsum5vpl
PubMed22210776
UniProtP16311|PEPT1_DERFA Peptidase 1 (Gene Name=DERF1)

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